Mesua beccariana (Clusiaceae), A Source of Potential Anti-cancer Lead Compounds in Drug Discovery
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چکیده
منابع مشابه
Mesua beccariana (Clusiaceae), a source of potential anti-cancer lead compounds in drug discovery.
An investigation on biologically active secondary metabolites from the stem bark of Mesua beccariana was carried out. A new cyclodione, mesuadione, along with several known constituents which are beccamarin, 2,5-dihydroxy-1,3,4-trimethoxy anthraquinone, 4-methoxy-1,3,5-trihydroxyanthraquinone, betulinic acid and stigmasterol were obtained from this ongoing research. Structures of these compound...
متن کاملIn Vitro Cytotoxic, Antioxidant, and Antimicrobial Activities of Mesua beccariana (Baill.) Kosterm., Mesua ferrea Linn., and Mesua congestiflora Extracts
The in vitro cytotoxicity tests on the extracts of Mesua beccariana, M. ferrea, and M. congestiflora against Raji, SNU-1, HeLa, LS-174T, NCI-H23, SK-MEL-28, Hep-G2, IMR-32, and K562 were achieved using MTT assay. The methanol extracts of Mesua beccariana showed its potency towards the proliferation of B-lymphoma cell (Raji). In addition, only the nonpolar to semipolar extracts (hexane to ethyl ...
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The cytotoxic structure-activity relationships among a series of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora were studied. Eleven xanthone derivatives identified as mesuarianone (1), mesuasinone (2), mesuaferrin A (3), mesuaferrin B (4), mesuaferrin C (5), 6-deoxyjacareubin (6), caloxanthone C (7), macluraxanthone (8), 1,5-dihydroxyxanthone (9), tovopyrifoli...
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Cyanophyta or cyanobacteria are a phylum of bacteria which obtain their energy by performing photosynthesis. Cyanobacteria are the oldest photosynthetic organisms that evolved on Earth approximately 2.6 to 3.5 billion years ago (Hedges, et al., 2001). They are generally called as bluegreen algae, which is a misnomer, as cyanobacteria are prokaryotic and algae are eukaryotic (Allaby, 1992). Cyan...
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Diabetes mellitus is a metabolic disease characterized by hyperglycaemia resulting from either defect in insulin secretion, insulin action, or both. Though, there exists many therapeutics for the treatment of diabetes, plant based drugs are generally considered safe and are much effective. However, traditional usage of medicinal plants for the treatment of diabetes lacks scientific validation. ...
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ژورنال
عنوان ژورنال: Molecules
سال: 2012
ISSN: 1420-3049
DOI: 10.3390/molecules170910791